BFORE (AV001) = Bosutinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia

Study title

BFORE (AV001) = Bosutinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Africa, Asia, Australia, Europe, North America]

Scientific title

A Multicenter Phase 3 Randomized, Open-Label Study of Bosutinib versus Imatinib in Adult Patients with Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia (EudraCT No. 2013-005101-31, clinicaltrials.gov NCT02130557)

Indication and most important inclusion criteria

Patients 18 years and older with molecular diagnosis of chronic phase CML can be enrolled within 6 months from initial diagnosis. Philadelphia chromosome status will be identified at screening. Both Philadelphia positive (Ph+) and Philadelphia negative (Ph-) patients may be included. Patients should have adequate function of liver, kidney and pancreas and an Eastern Cooperative Oncology Group (ECOG) Performance status of 0 or 1. Patients should be able to take oral tablets.

Short description of intervention

The aim of the study is to assess how well bosutinib works compared to imatinib in patients with newly diagnosed Philadelphia chromosome positive (Ph+) chronic phase (CP) chronic myelogenous leukemia (CML). The Major Molecular Response (MMR) rate of bosutinib at 12 months will be compared with that of imatinib. All patients will be treated and/or followed for 5 years (240 weeks) after randomization until the study has closed.

Type of study

First line trials

Current status

no longer recruiting

Study sponsor

Pfizer

Scientific lead / contact

To be communicated

Principal investigator

Europe:
Prof. Dr. med. Tim H. Brümmendorf


USA:
Dr. Jorge Eduardo Cortes, M.D.

Additional information

Study description in the EU Clinical Trials Register, which is hosted by the European Medicines Agency (EMA)

Study description in US register ClinicalTrials.gov, a service of the U.S. National Institutes of Health

Study centers / principal investigators

Australia

Adelaide, SA 5000
275 North Terrace
Tim Hughes

Bedford Park SA 5042
SA Pathology (at Flinders Medical Centre)
David Ross (Contact person: Kayleen Charles)

Box Hill, 3128
5 Arnold St
Anthony Schwarer

Frankston, 3199
Frankston Hospital
John Catalano

Kogarah, New South Wales, 2217
St George Hospital
Clinical Trials Unit-Cancer Services, Department of Clinical Haematology,
Dr. Shir-Jing Ho


Belgium

Gent, 9000
University Hospital of Gent (UZ Gent)
Prof. Lucien Noens

Leuven, 3000
UZ Leuven, Hematology Department
Prof. Gregor Verhoef

Liège, 4000
Hematology CHU de Liège - Hôpital du Sart-Tilman
Dr. Marie Lejeune

Verviers, 4800
Centre Hospitalier Peltzer La Tourelle (GHPLT) Verviers
Dr. Gaetan Vanstraelen


Canada

Ontario

Barrie, L4M 6M2
Royal Victoria Regional Health Centre
Dr. Rouslan Kotchetkov

Hamilton, L8V 5C2
Brian Leber

Oshawa, L1G 2B9
Durham Region Cancer Centre Lakeridge Health Oshawa
Dr. Ariah Schattner

Toronto, M5G 2M9
Medical Oncology and Hematology Princess Margaret
Dr. Jeffrey Lipton

New Brunswick

Internal Medicine Department
Moncton Hospital
Moncton, E1C 6Z8
Dr. Nizar Abdel-Samad

Quebec

Montreal, H1T 2M4
Lambert Busque

Quebec City, G1J 1Z4
CHU de Québec - Hôpital de l'Enfant-Jésus
Dr. Robert Delage

Saskatchewan

Saskatoon, S7N 4H4
Dr. Julie Stakiw

 

Czech Republic

Brno, 625 00
Fakultni Nemocnice Brno
Interni Hematoonkologicka a Onkologicka Klinika
Prof. Jiri Mayer

Hradec Kralove, 500 05
Fakultni Nemocnice Hradec Kralove, IV.
Interni Hematologicka Klinika
Dr. Petra Belohlavkova

Olomouc, 77520
Fakultní nemocnice Olomouc
Hematology - Oncology department
Edgar Faber

Prague, 128 08
Ustav Hematologie a Krevni Transfuze
Dr. Hana Klamova

Prague, 128 08
Vseobecna Fakultni Nemocnice Praha, I. Interni Klinika - Klinika Hematologie
Prof. Marek Trneny

 

Denmark

Aalborg, 9000
Aalborg University Hospital
Department of Hematology
Marianne Severinsen

Aarhus, 8000 C
Aarhus University Hospital
Department of Hematology
Prof. Jesper Stentoft

Odense, 5000
Odense University Hospital
Department of Hematology
Hanne Vestergaard

Roskilde, 4000
Roskilde Hospital
Department of Hematology
Dr. Lene Udby

 

Finland

Helsinki, 00029 HUS
M.D. Kimmo Porkka

 

France

Bordeaux, 33076
Service Oncologie Médicale Institut Bergonié- CRLCC
Dr. Gabriel Etienne

Le Chesnay cedex, 78157
Hôpital Mignot
Service Hematologie
Prof. Dr. med. Philippe Rousselot

Nantes cedex 1, 44093
CHU Nantes
Service Hematologie
Dr. med. Viviane Dubruille

Nice, 6202
Hopital l'Archet 1
Dr. Laurence Legros

Nîmes Cedex 9, 30029
Hématologie Clinique
Groupe Hospitalo-Universitaire Caremeau
Dr. Eric Jourdan

Pierre Benite, 69495
CHU Lyon Sud
Hématologie Prof. Dr. med. Mauricette Michallet

Poitiers, 86021
Haematology University Hospital of Poitiers
Cristina Precupanu

Strasbourg, 67000
Haematology St. Anne
M.D. Frederic Maloisel

Toulouse, 31059
Haematology CHU Purpan
Dr. Francoise Huguet (Dr. Travitian)


Germany

Aachen, 52074
Universitätsklinikum Aachen AÖR
Klinik für Onkologie, Hämatologie und Stammzelltransplantation (Med. Klinik IV)
Prof. Dr. med. Tim H. Brümmendorf

Berlin, 13353
Klinik für Innere Medizin mit Schwerpunkt Haematologie
Charité Berlin Campus Virchow Klinikum
Dr. Philipp Le Coutre

Bonn, 53127
Universitaetsklinikum Bonn
Medizinische Klinik 3
Onkologie, Hämatologie und Rheumatologie
Prof. Dr. Dominik Wolf

Dresden, 01307
Universitätsklinikum Carl Gustav Carus
Medizinische Klinik und Poliklinik I
PD Dr. Rainer Ordemann

Essen, 45147
Universitätsklinikum Essen (AOER)
Klinik für Hämatologie
PD Dr. Jürgen Novotny

Freiburg, 79106
Universitätsklinikum Freiburg
Klinik für Innere Medizin I

Hamburg, 20246
Universitätsklinikum Hamburg-Eppendorf
Hämatologie
Dr. Gunhild von Arnsberg

Jena, 07747
Universitätsklinikum Jena
Hämatologie
Prof. Dr. Andreas Hochhaus

Leipzig, 04103
Universitätsklinikum Leipzig AOER
Selbstständige Abt. für Hämatologie
Prof. Dr. Dietger Niederwieser

Magdeburg, 39194
Hämatologie und Onkologie Schwerpunktpraxis
PD Dr. med. Kathleen Jentsch-Ullrich

Mannheim, 68169
Medizinische Fakultät der Universität Mannheim
Dr. Susanne Saußele

 

Hungary

Budapest, 1083
Semmelweis Egyetem I. Belgyógyászat
Prof. Judit Demeter

Debrecen, 4032
Debreceni Egyetem Klinikai Központ, Belgyógyászati Inézet Hematológiai,
Tanszék
Prof. Dr. Árpád Illés

Gyor, 9023
Petz Aladár Megyei Oktató Kórház, II. dept. Internal Medicine-Haematology
Dr. Zoltán Gasztonyi

Kaposvár, 7400
Somogy Megyei Kaposi Mór Oktató Kórház
Hematológiai Osztály
Prof. Miklós Egyed

Szeged, 6723
Szegedi Tudományegyetem, Szent-Györgyi Albert Klinikai Központ, II. sz. Belgyógyászati Klinika és Kardiológiai Központ,
Hematológia
Professor Zita Borbényi

Szolnok, 5004
Jász-Nagykun-Szolnok Megyei Hetényi, Géza Kórház-Rendelőintézet
Dr. Gyorgy Ujj

 

Israel

Haifa, 35953
Hematology and Bone marrow transplant Rambam medical center
Dr. Noam Benyamini

Petah-Tikva, 49100
Rabin Medical Center; Hematology
Prof. Pia Raanani

 

Italy


Bergamo, 24127
A. O. Papa Giovanni XXIII
USC Ematologia
Prof. Alessandro Rambaldi

Bologna, 40138
Policlinico S. Orsola, Ematologia
Prof. Gianantonio Rosti
,

Cagliari, 09121
Oncology Department - Hematology Unit and BMT Centre - Armando Businco Hospital Cagliari
Dr. Emanuele Angelucci

Catania, 95124
Ospedale Ferrarotto - AOU Policlinico - V. Emanuele
Dr. Fabio Stagno

Firenze, 50134
Azienda Ospedaliero Universitaria Careggi - Ematologia
Prof. Alberto Bosi

Genova, 16132
IRCCS AOU San Martino -IST
Prof. Angelo Michele Carella

Milano, 20132
Ospedale San Raffaele,
Unità Operativa di Ematologia e Trapianto Midollo Osseo
Dr. Fabio Ciceri

Monza, 20900
Azienda Ospedaliera S. Gerardo Di Monza
Unità di Ricerca Clinica, Sezione di Ematologia
Prof. Carlo Gambacorti – Passerini

Napoli, 80122
Università Federico II, Div. di Ematologia /
Dip. Di Medicina Clinica e Chirurgica
Prof. Fabrizio Pane

Pescara, 65124
P.O. dello Spirito Santo
Dipartimento di Ematologia U.O. Ematologia
Dr. Paolo Di Bartolomeo

Reggio Calabria, 89124
Haematology Department Azienda Ospedaliera Bianchi Melacrino Morelli
Dr. Bruno Martino

Roma, 00144
Ospedale S. Eugenio, U.O. di Ematologia
Associated Professor Elisabetta Abruzzese

Venezia-Mestre, 30174
U.O. di Ematologia
Ospedale dell'Angelo
Prof. Renato Bassan

 

Mexico

Jalisco, 45170
Hospital General de Occidente
Departamento de Hematología
Dr. Carlos Roberto Best Aguilera

Mexico, D.F., 10700
Hospital Ángeles de Pedregal
Dr. Rafael Hurtado Monroy

Mexico, 11520
Hospital Español
Dr. José Luis Manuel Ayala Sánchez

Monterrey, NL, 6400
Monterrey International Research Center/
Hospital y Clinica Oca.
Dr. Enrique Baez de la Fuente

 

Netherlands

Amsterdam, 1081 HV
VU University Medical Center
Department of Hematology
Associated Professor Jeroen J.W.M. Janssen

Groningen, 9713 GZ
University Medical Center Groningen (UMCG)
Department of Hematology
Prof. Edo Vellenga

 

Norway

Bergen, 5020
Haukeland University Hospital
Depatment of Hematology
Prof. Dr. med. Bjørn Tore Gjertsen

Trondheim, 7006
St. Olavs Hospital
Avd for blodyskdommer
Dr. Henrik Hjorth-Hansen

 

Poland

Chorzów, 41-500
SPZOZ Zespol Szpitali Miejskich, w Chorzowie Oddzial Hematologiczny
Dr. Sebstian Grosicki

Gdansk, 80-952
Uniwersyteckie Centrum Kliniczne
Klinika Hematologii i Transplantologii
Prof. Andrzej Hellmann

Katowice, 40-032
Szpital Kliniczny im. A Mielęckiego, ŚUM w Katowicach, Oddział Hematologii i
Transplantacji Szpiku
Prof. Slawomira Kyrcz-Krzemien

Kraków, 31-501
Dr. Tomasz Sacha

Lodz, 93-510
Wojewódzki Szpital Specjalistyczny im M. Kopernika
Klinika Hematologii Uniwersytetu Medycznego
Prof. Tadeusz Robak

Lublin, 20-081
Katedra i Klinika Hematologii i Transplantacji Szpiku SPSK 1w Lublinie
Dr. Marek Hus

Warszawa, 02-774
Instytut Hematologii i Transfuzjologii, Klinika Hematologii
Prof. Krzysztof Warzocha

Wroclaw, 50-367
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu Katedra i Klinika Hematologii
Nowotworów Krwi i Transplantacji Szpiku
Prof. Kazimierz Kuliczkowski

 

Singapore

Singapore, 119228
Dept. of Haematology-Oncology
National University Hospital
Dr. Liang Piu Koh

Singapore, 169856
Singapore General Hospital
Dr. Charles Chuah

Singapore, 308433
Tan Tock Seng Hospital
Dr. Kiat Hoe Ong

 

Slovak Republic

Bratislava, 833 10
Narodny Onkologicky Ustav
Oddelenie Klinickej Hematologie
Dr. Ludmila Demitrovicova

Bratislava, 851 07
University Hospital Bratislava
Clinic of Hematology and Blood Transfusion
Associated Professor Martin Mistrik
(Contact person: Zuzana Sninska)

 

South Africa

Cape Town, 7925
UCT Private Academic Hospital
Division of Haematology
Nicolas Novitsky

Groenkloof, Gauteng, 0075
Mary Potter Oncology Centre
Dr. Graham L Cohen

Parktown, Gauteng, 2193
Wits Clinical Research
Prof. Paul Ruff

Pretoria, Gauteng, 0002
Department of Medical Oncology
Lydia Mary Dreosti

Saxonwold; Gauteng, 2196
Medical Oncology Centre Rosebank
Dr. Bernardo Leon Rapoport

 

South Korea

Anyang, 431-070
Hallym Sacred Heart Hospital
Internal Medicine
Prof. Dae-Young Zang

Busan, 602-715
Sung-Hyun Kim

Daegu, 700-712
Medicine Keimyung University
Dongsan Medical Center
Associated Professor Young-Rok Do

Jeonju, 561-712
Chonbuk National University Hospital
Division of Hematology
Professor Jae-Yong Kwak

Seoul, 110-746
Kangbuk Samsung Hospital
Internal Medicine
Associated Professor Suk-joong Oh

Seoul, 137-701
The Catholic University of Korea
Division of Hematology, Department of Internal Medicine Seoul St. Mary's Hospital
Prof. Dong-Wook Kim

 

Spain

Badalona, 08916
Hospital ICO - Germans Trias i Pujol, Unidad de Investigación Clínica de Hematología
Dr. Cristina Motllo

Barcelona, 08035
Hospital Vall d'Hebron
Haematology Department
Dr. Pere Barba

Barcelona, 08036
Hospital Clinic de Barcelona
Hematology Department
Dr. Francisco Cervantes

Madrid, 28006
Hospital Universitario La Princesa, Hematology and Hemotherapy
Prof. Juan Luis Steegmann

Madrid, 28007
Hospital General Universitario Gregorio Marañón
Haematology Department
Dr. Santiago Osorio Prendes

Madrid, 28034
Hospital Universitario Ramon y Cajal
Oncology
Dr. Valentin Garcia Gutierrez

Madrid, 28040
Hospital Clinico Universitario San Carlos Haematology
Dr. Ascension Pena

Salamanca, 37007
Hospital Universitario de Salamanca, Haematology Department
Dr. Fermin Sanchez-Guijo

Santiago de Compostela, 15706
Hospital Clinico Universitario de Santiago De Compostela
Haematology
Dr. Manuel Mateo Perez Encinas

Toledo, 45004
Hospital Virgen De La Salud
Haematology Department
Dr. Luis Felipe Casado Montero

Valencia, 46010
Hospital Clinico Universitario de Valencia (CHUV)
Hematology and Medical Oncology
Prof. Juan Carlos Hernandez-Boluda

 

Sweden

Linköping, 581 85
Linköping University Hospital
Dept. of Hematology
Dr. Dr. med. Kourosh Lotfi

Lund, 22185
Skåne University Hospital
Dept of Hematology and Vascular Disorders
Prof. Johan Richter

Örebro, 70185
University Hospital Örebro
Div. of Hematology
Mats Bjoereman

Stockholm, 17176
Karolinska University Hospital
Hematology
Associated Professor Leif Stenke

Umeå, 90185
Norrlands University Hospital
Hematological section
Dr. Berit Markevärn

Uppsala, 75185
Uppsala University Hospital
Department of Haematology
M.D. Ulla Olsson Stroemberg

 

Taiwan

Kaohsiung, 80756
Prof. Dr. Ta-Chih Liu
Tainan City, 710
M.D. Yin-Hsun Feng

Taipei, 10449
Mackay Memorial Hospital
Division of Hematology and Oncology, Department of Internal Medicine
Dr. Ken-Hong Lim

Taipei, 11217
Taipei Veterans General Hospital
Division of Hematology- Oncology
Dr. Jin-Hwang Liu

Taichung, 40447
China Medical University Hospital
Hematology and Oncology
Dr. Su-Peng Yeh

Taoyuan County, 33305
Professor Dr. Lee-Yung Shih

 

Thailand

Bangkok, 0000
Ratchathewi, Bangkok
Tontanai Numbenjapon

Bangkok, 10330
King Chulalongkorn Memorial Hospital
Division of Hematology
Department of Medicine
Udomsak U. Bunworasate

Bangkok, 10400
Ramathibodi Hospital
Division of Hematology
Department of Medicine
Ratchathewi
Dr. Pimjai Niparuck

Bangkok, 10700
Siriraj Hospital
Division of Hematology
Department of Medicine
Prof. Dr. Surapol S. Issaragrisil

Chiang Mai, 50200
Adisak A. Tantiworawi

 

Ukraine

Cherkasy, 18009
Municipal Institution "Cherkasy Regional Oncological Dispensary " of Cherkasy Regional Council
Regional Medical and Diagnostic Hematology Center
Dr. Halyna Pylypenko

Ivano-Frankivsk, 76008
Regional Clinical Hospital in Ivano-Frankivsk
Hematology Department
Associated Professor Nataliia Glushko

Khmel'nytsky, 29000
Khmelnytskyi Regional Hospital
Hematology Department
Dr. Grigoriy Rekhtman

Kyiv, 03115
State Institution "National scientific center of clinical radiology NAMS of Ukraine"
Radiation oncohematology and stem cells transplantation department of hematology and transplantology division within Clinical Radiology
Prof. Dr. Iryna Dyagil

Kyiv, 04112
Kyiv City Clinical Hospital #9
Hematology Department #1
Dr. Svitlana Kalinina

Lviv, 79044
State Institution "Institute of Blood Pathology and Transfusion Medicine NAMS of Ukraine"
Hematology Department
Prof. Dr. Zvenyslava Maslyak

 

UK

Birmingham, B9 5SS
Birmingham Heartlands Hospital
Dr. Joanne Ewing

Cardiff, CF14 4XW
Haematology Department
University Hospital of Wales
Dr. Jonathan Kell

Leeds, LS9 7TF
St James Hospital
LCRF (Haematology)
Dr. Graeme Murray Smith
Stewart McConnell
Myeloid Research Nurse

Leicester, LE1 5WW
Leicester Royal Infirmary
HOPE Clinical Trials Unit
Dr. Ann Hunter

Liverpool, L7 8XP
Royal Liverpool University Hospital
Haematology Department
Professor Richard Clark

London, W12 0HS
Haematology Hammersmith Hospital
Catherine Lewis Centre
Dr. Dragana Milojkovic

Nottingham; NG5 1PB
Nottingham University Hospitals NHS Trust – City Campus
Dept. of Clinical Oncology
Dr. Jennifer Byrne

Oxford, OX3 7 LE
Oxford Cancer and Haematology Centre
Churchill Hospital
Dr. Adam Mead

Sheffield, S10 2JF
Royal Hallamshire Hospital
Sameer Tulpule

 

USA

Alabama
Mobile, Alabama 36604
Clinical Trials Department
Thomas W Butler

Arkansas
Hot Springs, Arkansas 71913
Genesis Cancer Center
Dr. R. Timothy Webb

California
Anaheim, California 92801
Pacific Cancer Medical Center Inc.
Ajit S Maniam

Connecticut
Southington, Conneticut 06489
Cancer Center of Central Connecticut
Dr. Peter D. Byeff

Georgia
Atlanta, Georgia 30322
Winship Cancer Institute of Emory University
Hematology and Medical Oncology
Dr. Vamsi K. Kota

Hawaii
Honolulu, Hawaii 96819
Jennifer F. Carney

Illinois
Chicago, Illinois 60612
Hematology & Oncology John H. Stroger, Jr. Hospital of Cook County
Dr. Rosalind Catchatourian
(Contact Person: Dr. Augustin Haidau)

Chicago, Illinois 60612
Rush University Medical Center
Dr. Jamile M. Shammo


Chicago, Illinois 60612
M.D. Irum Khan

Maywood, Illinois 60153
Aileen Go

Indiana
Boise, Indiana 83706
Saint Alphonsus Health System
Dr. Kerry Pulver

Indianapolis, 46237
Indiana Blood & Marrow Transplantation
Dr. Luke Akard

Louisiana
Lafayette, Louisiana 70503
Dr. Salman Malad

Shreveport, Louisiana 71103
Feist-Weiller Cancer Center
LSU Health Sciences Center
Dr. Reinhold Munker

Maryland
Bethesda, Maryland 20817
Center for Cancer and Blood Disorders
Dr. Ralph Boccia

Massachusetts
Worcester, Massachusetts 01655
UMass Memorial Medical Center
Dr. Jan Cerny

Michigan
Ann Arbor, Michigan 48106
St. Joseph's Mercy Hospital
Dr. Christopher Reynolds

Ann Arbor, Michigan 48109
University of Michigan
M.D. Moshe Talpaz

Grosse Pointe Woods, Michigan 48236
St. John Health
Van Elslander Cancer Center
Dr. Carrie L. Dul

Minnesota
Saint Louis Park, Minnesota 55416
Metro MN CCOP
Dr. Daniel Anderson

Mississippi
Tupelo, Mississippi 38801
North Mississippi Hematology and Oncology Assoc., Ltd.
Dr. Andrew Kellum

Missouri
Kansas City, Missouri 64131
Dr. Kelly B Pendergrass

Nebraska
Omaha, Nebraska 68114
Dr. Stefano Tarantolo

New Jersey
Hackensack, New Jersey 07601
Hackensack University Medical Center
John Theurer Cancer Center
Dr. Stefan Faderl

New Mexico
Farmington, New Mexico 87401
San Juan Oncology Associates
Dr. Jeffrey Neidhart

New York
Mineola, New York 11501
Winthrop University Hospital
Michael E. Garrison

New York, New York 10003
Mount Sinai Beth Israel Medical Center
Phillips Ambulatory Care Center
Dr. Ilan Shapira

New York, New York 10021
Memorial Sloan-Kettering Cancer
Dr. Michael J. Mauro

Rochester, New York 14642
University of Rochester Medical Center
James P. Wilmot Cancer Center
Jason H. Mendler

Syracuse, New York 13210
Upstate Medical University
Bernard J. Poiesz

North Carolina
Durham, North Carolina 27710
Dr. David A Rizzieri

Pinehurst, North Carolina 28374
FirstHealth Out Patient Cancer Center
Charles Kuzma

Ohio
Cleveland, Ohio 44106
University Hospitals
Brenda W. Cooper

Cincinnati, Ohio 45267
Stephen Medlin

Pennsylvania
Gettysburg, Pennsylvania 17325
Gettysburg Cancer Center
Dr. Satish Shah

South Carolina
Charleston, South Carolina 29425
Hollings Cancer Center Medical University of South Carolina
Dr. Alice Mims

Greenville, South Carolina 29615
Greenville Health System
M.D. Saeeda Chowdhury

Tennessee
Associates In Oncology and Hematology
Chattanooga, Tennessee 37421
Dr. Jitendra Gandhi

Texas
Houston, Texas 77030
MD Anderson Cancer Center
M.D. Jorge Cortes
(Contact person: Maria "Cookie" Gavino)

Utah
Salt Lake City, Utah 84106
IHO Corp/ Utah Cancer Specialists
Dr. Stephen Kendall

Salt Lake City, Utah 84112
The University of Utah
Huntsman Cancer Institute
Michael W. Deininger

Washington
Seattle, Washington 98101
David Aboulafia

Seattle, Washington 98109
Dr. Vivian Oehler

Wisconsin
Green Bay, Wisconsin 54303
Green Bay Oncology
Dr. Anthony Jaslowski

Milwaukee, Wisconsin 53226
Ehab Atallah